{"id":1066,"date":"2023-11-03T06:10:07","date_gmt":"2023-11-03T05:10:07","guid":{"rendered":"https:\/\/hjs.erpaweb-dev.de\/products-services\/ames-kits\/microames6-test\/"},"modified":"2023-11-03T06:12:06","modified_gmt":"2023-11-03T05:12:06","slug":"microames6-test","status":"publish","type":"page","link":"https:\/\/www.hjs-consulting.com\/en\/products-services\/ames-kits\/microames6-test\/","title":{"rendered":"MicroAmes6 Test"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1066\" class=\"elementor elementor-1066 elementor-1055\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-21826ab elementor-section-full_width elementor-section-height-min-height elementor-section-height-default elementor-section-items-middle\" data-id=\"21826ab\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_opacity_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_opacity_range&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:&quot;51&quot;,&quot;end&quot;:&quot;76&quot;}},&quot;background_motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;background_motion_fx_opacity_direction&quot;:&quot;in-out&quot;,&quot;background_motion_fx_opacity_level&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;background_motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-71811d07\" data-id=\"71811d07\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-19e11b60 elementor-widget elementor-widget-heading\" data-id=\"19e11b60\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Principle of the MicroAmes6 Test <\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6b89b5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a6b89b5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-32eb7e13\" data-id=\"32eb7e13\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5b9ccad3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5b9ccad3\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-74979a49\" data-id=\"74979a49\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3964bf6d elementor-widget elementor-widget-text-editor\" data-id=\"3964bf6d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The <strong>MicroAmes6 kit<\/strong> includes reagents for the bacterial reverse mutation test: Point mutations were made in the histidine (Salmonella typhimurium) operon, rendering the bacteria incapable of producing the corresponding amino acid. These mutations result in his- organisms that cannot grow unless histidine is supplied.<\/p>\n<p>A test sample\u2019s mutagenic potential is assessed by exposing these amino acid-requiring organisms to varying concentrations of sample and selecting for the reversion event. Media lacking the specific amino acid are used for this selection which allow only those cells that have undergone the reversion to histidine prototrophy to survive and grow. A mutagenic event causing base substitutions or frameshifts within the gene may cause a reversion to amino acid prototrophy. These reverted bacteria will then grow in histidine-deficient media whereas non reverted bacteria will not be able to grow.<\/p>\n<p>The strains provided in this kit are the Salmonella typhimurium strain TA98 strain, suitable for the detection of frameshift mutations, and TA100, which detects base-pair substitution mutations.<\/p>\n<p>The kit content and all associated reagents meet the requirements of the OECD guideline 471 for testing chemicals.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Principle of the MicroAmes6 Test The MicroAmes6 kit includes reagents for the bacterial reverse mutation test: Point mutations were made in the histidine (Salmonella typhimurium) operon, rendering the bacteria incapable of producing the corresponding amino acid. These mutations result in his- organisms that cannot grow unless histidine is supplied. A test sample\u2019s mutagenic potential is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":916,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-1066","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>MicroAmes6 Test - hjs consulting<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hjs-consulting.com\/en\/products-services\/ames-kits\/microames6-test\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MicroAmes6 Test - hjs consulting\" \/>\n<meta property=\"og:description\" content=\"Principle of the MicroAmes6 Test The MicroAmes6 kit includes reagents for the bacterial reverse mutation test: Point mutations were made in the histidine (Salmonella typhimurium) operon, rendering the bacteria incapable of producing the corresponding amino acid. 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